Programme


Thursday 12 December

 

08:30         

Registration 

08:50 

Welcome 

09:00

(invited) microRNAs decrease gene expression noise
A van Oudenaarden, Hubrecht Institute-KNAW & University Medical Center Utrecht, Netherlands

09:35

Transcription-induced supercoiling and topological domains in eukaryotic chromosomes
A Stasiak, University of Lausanne, Switzerland

09:55

Memory accelerates bacterial adaptation in fluctuating environments
E Kussell, New York University, US

10:15

Coffee

10:45

(invited) How growing populations compete for space: lessons from bacteria?
R Allen, University of Edinburgh, UK

11:15

Analytic results and mechanistic inference for the mtDNA bottleneck suggest that upregulating mitophagy may combat inherited disease
I Johnston, Imperial College London, UK

11:35

Brownian dynamics simulations reveal a generic mechanism for the clustering of DNA binding proteins
C Brackley, University of Edinburgh, UK

11:55

Flash posters 1

12:30

Lunch

13:45

Flash posters 2

14:45

(invited) Propagation of phenotypic variability within bacterial lineages
A Lindner, INSERM and Paris Descartes University, France

15:15

Refreshment break

15:45

(invited) Using single-cell RNA-sequencing to study heterogeneity in gene expression
J Marioni, EMBL-EBI, UK

16:15

Extensive oscillatory gene expression during C. elegans larval development
G-J Hendriks, Friedrich Miescher Institute for Biomedical Research, Switzerland

16:35

Functional and spatial characterisation of chromatin states in S. cerevisiae
S Sewitz, The Babraham Institute, UK

16:55

(Invited) From gene expression patterns to dynamical models of limb development
J Sharpe, EMBL-CRG Systems Biology Unit, Spain

17:25

End of day 1

19:00

Dinner

Friday 13 December

 

09:00         

(invited) Modelling large-scale organization of chromatin: a tale of the HoxB locus organization in mouse ES cells
A Pombo, MRC Clinical Services Centre, UK and Berlin Institute for Medical Systems Biology, Germany

09:30

Concerted control of E. coli cell division
M Osella, University of Torino, Italy

09:50

Super-resolution imaging of transcription in live cells
M Stracy, Oxford University, UK

10:10

Coffee

10:45

(invited) Mathematical modelling of dorsoventral patterning in the vertebrate neural tube
K Page, University College London, UK

11:15

A mechanistic model of cellular growth
A Weisse, SynthSys - Synthetic & Systems Biology, University of Edinburgh, UK

11:35

Transcriptional reprogramming following gene deletion and compensatory evolution in yeast
B Papp, Biological Research Centre of the Hungarian Academy of Sciences, Hungary

11:55

(invited) Dynamic changes of the 3D chromatin interactome during cell differentiation
W Huber, EMBL, Germany

12:25

Lunch

13:45

(invited) Chromatin and gene regulation in stem cell populations and during development
W A Bickmore, MRC Human Genetics Unit, University of Edinburgh, UK

14:15

Genomic analysis reveals epistatic silencing of "expensive" genes in Escherichia coli K-12
R Srinivasan, National Centre for Biological Sciences, India

14:35

Autoregulation of a eukaryotic transposon
K Lipkow, Babraham Institute & University of Cambridge, UK

14:55

Computational and genetic reduction of a cell cycle to its simplest, primordial components
S Murray, John Innes Centre, UK

15:15

Refreshment break

15:45

Predicting genomic occupancy of transcription factors with biophysical models
N R Zabet, Cambridge Systems Biology Centre, University of Cambridge, UK

16:05

System-level characterization of molecular determinants of gene expression noise
G Chalancon, MRC LMB, UK

16:25

(invited) Mouse spermatogenic stem cell self-renewal
B Simons, University of Cambridge, UK

16:55

Close

 

Flash posters

Noisy neighbors: analyzing the role of the genomic features in the control of gene expression stochasticity
O Gandrillon, CNRS

Towards a quantitative analysis of Competing Endogenous RNA interactions
C Bosia, Human Genetics Foundation - Torino

Multimodality and flexibility of stochastic gene expression
G Innocentini, Institute of Mathematics and Statistics from University of São Paulo (IME - USP)

Noise-induced bimodality in gene regulatory networks
P Thomas, University of Edinburgh, UK

Spatial organization of cytoplasmic protein clusters in bacteria
A Scialdone, John Innes Centre, UK

Transient solutions of master equations
J Dattani, Imperial College London, UK

Use of a combined experimental-mathematical approach to predict novel gene regulatory activity by HGF, a cancer-associated stroma-derived growth factor
A Konstorum, University of California, Irvine, USA

Buffered Qualitative Stability explains why transcriptional networks are robust and evolvable
L Albergante, College of Life Sciences, University of Dundee, UK

Combination of signalling network and promoter architecture determines variation dynamics in gene expression regulation
A Granados, Imperial College London, UK

Trans-splicing as a by-product of the transcription of multiple genes at shared transcription factories
R Beagrie, MRC CSC

Quantitative analysis of DNA microarray data from physical principles
E Carlon, Institute for Theoretical Physics, Belgium

The car parking model solves the random completion problem in DNA replication
J Karschau, University of Aberdeen, UK

ALCATRAS: A microfluidic system for timelapse microscopy of budding yeast
E Bakker, University of Edinburgh, UK

A mechanistic model with random forcing describes multiple Sclerosis course and helps understand its pathogenesis
V A G Ricigliano, Sapienza University of Rome, Italy

Dynamics of chromosomal loci
A Javer, University of Cambridge, UK

Negotiating nutrient transitions in E. Coli : Single cell responses to global shifts
E Nugent, University of Cambridge, UK

Single-cell analysis of a development transition using live cell imaging
A Miermont, University College London, UK


Key dates

  • Abstract submission deadline (extended):
    6 September 2013
  • Early registration deadline:
    27 September 2013
  • Registration deadline:
    4 December 2013